Sequence Detail

ID/Version

O54879 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=High mobility group protein B3;AltName: Full=High mobility group protein 2a; Short=HMG-2a;AltName: Full=High mobility group protein 4; Short=HMG-4;

Provider

SWISS-PROT

Sequence

Polypeptide 200 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hmgb3	high mobility group box 3	13	112	4	8

Sequence references in MGI

J:47656 Vaccari T, et al., Hmg4, a new member of the Hmg1/2 gene family. Genomics. 1998 Apr 15;49(2):247-52
J:84890 Nemeth MJ, et al., Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood. 2003 Aug 15;102(4):1298-306
J:96514 Nemeth MJ, et al., Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood. 2005 Jan 15;105(2):627-34
J:113745 Nemeth MJ, et al., Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation. Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13783-8
J:154027 Yanai H, et al., HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature. 2009 Nov 5;462(7269):99-103
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89