Sequence Detail

ID/Version

O54829 E9QLB9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Regulator of G-protein signaling 7; Short=RGS7;

Provider

SWISS-PROT

Sequence

Polypeptide 469 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rgs7	regulator of G protein signaling 7	42	98	4	11

Sequence references in MGI

J:53422 He W, et al., RGS9, a GTPase accelerator for phototransduction. Neuron. 1998 Jan;20(1):95-102
J:96916 Martemyanov KA, et al., R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. J Biol Chem. 2005 Feb 18;280(7):5133-6
J:100172 Drenan RM, et al., Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. J Cell Biol. 2005 May 23;169(4):623-33
J:185272 Orlandi C, et al., GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J Cell Biol. 2012 Jun 11;197(6):711-9
J:232911 Orlandi C, et al., Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain. J Biol Chem. 2015 May 29;290(22):13622-39
J:278859 Orlandi C, et al., Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors. Neuropsychopharmacology. 2019 Feb;44(3):642-653
J:281109 Song C, et al., The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex. J Biol Chem. 2019 Aug 30;294(35):13145-13157
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89