Sequence Detail

ID/Version

O54804 Q8BPL3 Q9QX56 Q8BPW6 Q9CXP3 G5E853 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Choline kinase alpha; Short=CK; EC=2.7.1.32 {ECO:0000250|UniProtKB:P35790};AltName: Full=CHETK-alpha;AltName: Full=Ethanolamine kinase; Short=EK; EC=2.7.1.82 {ECO:0000250|UniProtKB:P35790};

Provider

SWISS-PROT

Sequence

Polypeptide 453 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chka	choline kinase alpha	56	102	3	18

Sequence references in MGI

J:49279 Aoyama C, et al., Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs. Biochim Biophys Acta. 1998 Jul 31;1393(1):179-85
J:61502 Aoyama C, et al., Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta. J Lipid Res. 2000 Mar;41(3):452-64
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110329 Liao H, et al., Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta. Biochim Biophys Acta. 2006 Jan;1761(1):111-20
J:130726 Wu G, et al., Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis. J Biol Chem. 2008 Jan 18;283(3):1456-62
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89