Sequence Detail

ID/Version

O54794 Q8C630 (UniProt | EBI)

Last sequence update: 1998-06-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Aquaporin-7 {ECO:0000305|PubMed:15591341}; Short=AQP-7;AltName: Full=Aquaglyceroporin-7;

Provider

SWISS-PROT

Sequence

Polypeptide 303 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aqp7	aquaporin 7	46	112	5	16

Sequence references in MGI

J:95278 Maeda N, et al., Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17801-6
J:98734 Hara-Chikuma M, et al., Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation. J Biol Chem. 2005 Apr 22;280(16):15493-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100477 Hibuse T, et al., Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10993-8
J:102454 Sohara E, et al., Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice. Am J Physiol Renal Physiol. 2005 Dec;289(6):F1195-200
J:125011 Matsumura K, et al., Aquaporin 7 Is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion. Mol Cell Biol. 2007 Sep;27(17):6026-37
J:147631 Skowronski MT, et al., AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism. Am J Physiol Renal Physiol. 2007 Mar;292(3):F956-65
J:220015 Miyauchi T, et al., Dynamic subcellular localization of aquaporin-7 in white adipocytes. FEBS Lett. 2015 Feb 27;589(5):608-14
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89