Sequence Detail

ID/Version

O54785 Q9QUL4 O54776 O55238 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=LIM domain kinase 2; Short=LIMK-2; EC=2.7.11.1 {ECO:0000250|UniProtKB:P53671};

Provider

SWISS-PROT

Sequence

Polypeptide 638 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Limk2	LIM domain kinase 2	36	119	3	95

Sequence references in MGI

J:44929 Koshimizu U, et al., cDNA cloning, genomic organization, and chromosomal localization of the mouse LIM motif-containing kinase gene, Limk2. Biochem Biophys Res Commun. 1997 Dec 18;241(2):243-50
J:45560 Ikebe C, et al., Mouse LIM-kinase 2 gene: cDNA cloning, genomic organization, and tissue-specific expression of two alternatively initiated transcripts. Genomics. 1997 Dec 15;46(3):504-8
J:47751 Ikebe C, et al., Identification of testis-specific (Limk2t) and brain-specific (Limk2c) isoforms of mouse LIM-kinase 2 gene transcripts. Biochem Biophys Res Commun. 1998 May 19;246(2):307-12
J:49172 Takahashi H, et al., A novel transcript encoding truncated LIM kinase 2 is specifically expressed in male germ cells undergoing meiosis. Biochem Biophys Res Commun. 1998 Aug 10;249(1):138-45
J:137325 Ding Y, et al., Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion. Mol Cell Biol. 2008 Jun;28(11):3742-56
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89