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Sequence Detail
ID/Version
O35943 (UniProt | EBI) Last sequence update: 1998-01-01
Last annotation update: 2019-05-08
Sequence
description
from provider
RecName: Full=Frataxin, mitochondrial; Short=Fxn; EC=1.16.3.1;Contains: RecName: Full=Frataxin intermediate form;Contains: RecName: Full=Frataxin mature form;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 207 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fxn frataxin 60 6 9 19
Sequence references in MGI J:42050 Koutnikova H, et al., Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin. Nat Genet. 1997 Aug;16(4):345-51
J:129870 Martelli A, et al., Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues. Hum Mol Genet. 2007 Nov 15;16(22):2651-8
J:151779 Calmels N, et al., The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia. PLoS One. 2009;4(7):e6379
J:153234 Huang ML, et al., Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16381-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory