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Sequence Detail
ID/Version
O35379 (UniProt | EBI) Last sequence update: 1998-01-01
Last annotation update: 2019-12-11
Sequence
description
from provider
RecName: Full=Multidrug resistance-associated protein 1 {ECO:0000305}; EC=7.6.2.2 {ECO:0000269|PubMed:9281595};AltName: Full=ATP-binding cassette sub-family C member 1;AltName: Full=Glutathione-S-conjugate-translocating ATPase ABCC1 {ECO:0000305};
Provider SWISS-PROT
Sequence
Polypeptide 1528 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 63 6 7 18
Sequence references in MGI J:34847 Stride BD, et al., Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter. Mol Pharmacol. 1996 Jun;49(6):962-71
J:43236 Stride BD, et al., Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. Mol Pharmacol. 1997 Sep;52(3):344-53
J:44110 Wijnholds J, et al., Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nat Med. 1997 Nov;3(11):1275-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory