Sequence Detail

ID/Version

O35298 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Acyloxyacyl hydrolase {ECO:0000303|Ref.1}; EC=3.1.1.77 {ECO:0000305|PubMed:12810692, ECO:0000305|PubMed:15155618, ECO:0000305|PubMed:17322564, ECO:0000305|PubMed:18779055, ECO:0000305|PubMed:19860560};Contains: RecName: Full=Acyloxy

Provider

SWISS-PROT

Sequence

Polypeptide 574 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aoah	acyloxyacyl hydrolase	28	97	2	24

Sequence references in MGI

J:90249 Feulner JA, et al., Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract. Infect Immun. 2004 Jun;72(6):3171-8
J:90493 Lu M, et al., Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells. J Exp Med. 2003 Jun 16;197(12):1745-54
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121874 Shao B, et al., A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen. J Biol Chem. 2007 May 4;282(18):13726-35
J:247934 Zou B, et al., Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury. PLoS Pathog. 2017 Jun;13(6):e1006436
J:283185 Gorelik A, et al., Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E896-E905