Sequence Detail

ID/Version

O35295 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcriptional regulator protein Pur-beta;AltName: Full=Purine-rich element-binding protein B;AltName: Full=Vascular actin single-stranded DNA-binding factor 2 p44 component;

Provider

SWISS-PROT

Sequence

Polypeptide 324 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Purb	purine rich element binding protein B	41	98	4	0

Sequence references in MGI

J:53004 Kelm RJ Jr, et al., Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta. J Biol Chem. 1997 Oct 17;272(42):26727-33
J:55001 Kelm RJ Jr, et al., Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter. J Biol Chem. 1999 May 14;274(20):14238-45
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:343118 Rumora AE, et al., Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element-Binding Protein B. Biochemistry. 2016 May 17;55(19):2794-805
J:343120 Jia L, et al., Purbeta promotes hepatic glucose production by increasing Adcy6 transcription. Mol Metab. 2020 Jan;31:85-97
J:343405 Ferris LA, et al., Purine-rich element binding protein B attenuates the coactivator function of myocardin by a novel molecular mechanism of smooth muscle gene repression. Mol Cell Biochem. 2021 Aug;476(8):2899-2916