Sequence Detail

ID/Version

O35286 Q99L91 (UniProt | EBI)

Last sequence update: 2003-06-06
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=ATP-dependent RNA helicase DHX15 {ECO:0000305}; EC=3.6.4.13 {ECO:0000250|UniProtKB:O43143};AltName: Full=DEAH box protein 15 {ECO:0000303|PubMed:9342318};

Provider

SWISS-PROT

Sequence

Polypeptide 795 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dhx15	DEAH-box helicase 15	52	103	3	47

Sequence references in MGI

J:43702 Gee S, et al., Cloning of mDEAH9, a putative RNA helicase and mammalian homologue of Saccharomyces cerevisiae splicing factor Prp43. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11803-7
J:227056 Wang P, et al., Nlrp6 regulates intestinal antiviral innate immunity. Science. 2015 Nov 13;350(6262):826-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302140 Wang Y, et al., The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017432118
J:306634 Xing J, et al., DHX15 is required to control RNA virus-induced intestinal inflammation. Cell Rep. 2021 Jun;35
J:316943 Shen C, et al., Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome. Cell. 2021 Nov 11;184(23):5759-5774.e20