Sequence Detail

ID/Version

O35253 O88709 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Mothers against decapentaplegic homolog 7; Short=MAD homolog 7; Short=Mothers against DPP homolog 7;AltName: Full=Mothers against decapentaplegic homolog 8; Short=MAD homolog 8; Short=Mothers against DPP homol

Provider

SWISS-PROT

Sequence

Polypeptide 426 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Smad7	SMAD family member 7	116	113	3	81

Sequence references in MGI

J:43278 Nakao A, et al., Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling [see comments]. Nature. 1997 Oct 9;389(6651):631-5
J:87112 Koinuma D, et al., Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7. EMBO J. 2003 Dec 15;22(24):6458-6470
J:198828 Kelly CE, et al., Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538