Sequence Detail

ID/Version

O35182 Q9CW62 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Mothers against decapentaplegic homolog 6; Short=MAD homolog 6; Short=Mothers against DPP homolog 6;AltName: Full=Mad homolog 7;AltName: Full=SMAD family member 6; Short=SMAD 6; Short=Smad6;

Provider

SWISS-PROT

Sequence

Polypeptide 495 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Smad6	SMAD family member 6	90	115	4	26

Sequence references in MGI

J:43279 Imamura T, et al., Smad6 inhibits signalling by the TGF-beta superfamily [see comments]. Nature. 1997 Oct 9;389(6651):622-6
J:87112 Koinuma D, et al., Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7. EMBO J. 2003 Dec 15;22(24):6458-6470
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:198828 Kelly CE, et al., Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538