Sequence Detail

ID/Version

O35084 (UniProt | EBI)

Last sequence update: 1998-07-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; EC=1.14.15.18 {ECO:0000269|PubMed:10092858};AltName: Full=25-OHD-1 alpha-hydroxylase;AltName: Full=25-hydroxyvitamin D(3) 1-alpha-hydroxylase; Short=VD3 1A hydroxylase;A

Provider

SWISS-PROT

Sequence

Polypeptide 507 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	73	108	3	12

Sequence references in MGI

J:43146 Takeyama K, et al., 25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis. Science. 1997 Sep 19;277(5333):1827-30
J:101035 Yamamoto K, et al., Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1. J Biol Chem. 2005 Aug 26;280(34):30511-6