Sequence Detail

ID/Version

O35047 Q3V035 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Homologous-pairing protein 2 homolog;AltName: Full=PSMC3-interacting protein;AltName: Full=Proteasome 26S ATPase subunit 3-interacting protein;AltName: Full=Tat-binding protein 1-interacting protein; Short=TBP-1-interacting protein;

Provider

SWISS-PROT

Sequence

Polypeptide 217 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psmc3ip	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein	30	99	3	11

Sequence references in MGI

J:43564 Tanaka T, et al., Molecular cloning and characterization of a novel TBP-1 interacting protein (TBPIP):enhancement of TBP-1 action on Tat by TBPIP. Biochem Biophys Res Commun. 1997 Oct 9;239(1):176-81
J:92384 Enomoto R, et al., Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated homologous pairing. J Biol Chem. 2004 Aug 20;279(34):35263-72
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109004 Petukhova GV, et al., The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis. Dev Cell. 2003 Dec;5(6):927-36
J:114577 Pezza RJ, et al., Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex. J Biol Chem. 2006 Jul 7;281(27):18426-34
J:121894 Ploquin M, et al., Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases. Nucleic Acids Res. 2007;35(8):2719-33
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:330108 Pezza RJ, et al., Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing. Genes Dev. 2007 Jul 15;21(14):1758-66