Sequence Detail

ID/Version

O09173 Q7TPP2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Homogentisate 1,2-dioxygenase; EC=1.13.11.5 {ECO:0000269|PubMed:7705358};AltName: Full=Homogentisate oxygenase;AltName: Full=Homogentisic acid oxidase;AltName: Full=Homogentisicase;

Provider

SWISS-PROT

Sequence

Polypeptide 445 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hgd	homogentisate 1, 2-dioxygenase	21	101	3	8

Sequence references in MGI

J:38924 Schmidt SR, et al., Cloning of the homogentisate 1,2-dioxygenase gene, the key enzyme of alkaptonuria in mouse. Mamm Genome. 1997 Mar;8(3):168-71
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:320064 Schmidt SR, et al., Murine liver homogentisate 1,2-dioxygenase. Purification to homogeneity and novel biochemical properties. Eur J Biochem. 1995 Mar 1;228(2):425-30