Sequence Detail

ID/Version

O09009 B1ATU3 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Beta-1,3-N-acetylglucosaminyltransferase radical fringe {ECO:0000305}; EC=2.4.1.222 {ECO:0000269|PubMed:16221665};AltName: Full=O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;

Provider

SWISS-PROT

Sequence

Polypeptide 332 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rfng	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	22	110	3	5

Sequence references in MGI

J:41128 Johnston SH, et al., A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development. 1997 Jun;124(11):2245-54
J:41258 Cohen B, et al., Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila. Nat Genet. 1997 Jul;16(3):283-8
J:55076 Moran JL, et al., Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes. Mamm Genome. 1999 Jun;10(6):535-41
J:105687 Rampal R, et al., Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats. J Biol Chem. 2005 Dec 23;280(51):42454-63
J:243509 Kakuda S, et al., Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands. Dev Cell. 2017 Jan 23;40(2):193-201