Sequence Detail

ID/Version

O08934 Q78DU3 P70457 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Homeobox protein unc-4 homolog;AltName: Full=Homeobox protein Uncx4.1;

Provider

SWISS-PROT

Sequence

Polypeptide 530 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uncx	UNC homeobox	16	172	4	3

Sequence references in MGI

J:35788 Rovescalli AC, et al., Cloning and characterization of four murine homeobox genes. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10691-6
J:42585 Mansouri A, et al., Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Dev Dyn. 1997 Sep;210(1):53-65
J:54606 Barrantes IB, et al., Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse. Curr Biol. 1999 May 6;9(9):470-80
J:58409 Horikawa K, et al., Adhesive subdivisions intrinsic to the epithelial somites. Dev Biol. 1999 Nov 15;215(2):182-9
J:62022 Leitges M, et al., The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development. 2000 Jun;127(11):2259-67
J:62023 Mansouri A, et al., Uncx4.1 is required for the formation of the pedicles and proximal ribs and acts upstream of Pax9. Development. 2000 Jun;127(11):2251-8
J:72525 Schubert FR, et al., Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites. Dev Dyn. 2001 Nov;222(3):506-21
J:75945 Nomura-Kitabayashi A, et al., Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development. 2002 May;129(10):2473-81
J:106094 Asbreuk CH, et al., Neurohypophysial dysmorphogenesis in mice lacking the homeobox gene Uncx4.1. J Mol Endocrinol. 2006 Feb;36(1):65-71
J:110233 Nakajima Y, et al., Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2. Development. 2006 Jul;133(13):2517-25
J:121562 Takahashi Y, et al., Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation. Dev Dyn. 2007 Jun;236(6):1484-94
J:122747 Chan T, et al., Ripply2 is essential for precise somite formation during mouse early development. FEBS Lett. 2007 Jun 12;581(14):2691-6