Sequence Detail

ID/Version

O08760 O08910 O35617 O08733 O35915 Q9QXE8 O08991 (UniProt | EBI)

Last sequence update: 2000-12-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=N-glycosylase/DNA lyase;Includes: RecName: Full=8-oxoguanine DNA glycosylase; EC=3.2.2.-;Includes: RecName: Full=DNA-(apurinic or apyrimidinic site) lyase; Short=AP lyase; EC=4.2.99.18;

Provider

SWISS-PROT

Sequence

Polypeptide 345 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ogg1	8-oxoguanine DNA-glycosylase 1	62	97	3	20

Sequence references in MGI

J:40805 Aburatani H, et al., Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Cancer Res. 1997 Jun 1;57(11):2151-6
J:41160 Lu R, et al., A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr Biol. 1997 Jun 1;7(6):397-407
J:41749 Rosenquist TA, et al., Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7429-34
J:45415 Tani M, et al., Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage. Mamm Genome. 1998 Jan;9(1):32-7