Sequence Detail

ID/Version

O08750 Q497U0 Q3ULK2 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Nuclear factor interleukin-3-regulated protein;AltName: Full=E4 promoter-binding protein 4;AltName: Full=Embryo implantation-related NFIL3/E4BP4-like transcription factor;

Provider

SWISS-PROT

Sequence

Polypeptide 462 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nfil3	nuclear factor, interleukin 3, regulated	37	109	3	20

Sequence references in MGI

J:69935 Ikushima S, et al., Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2609-14
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:120341 Ohno T, et al., The negative transcription factor E4BP4 is associated with circadian clock protein PERIOD2. Biochem Biophys Res Commun. 2007 Mar 23;354(4):1010-5
J:271698 Zhao M, et al., E4bp4 regulates carboxylesterase 2 enzymes through repression of the nuclear receptor Rev-erbalpha in mice. Biochem Pharmacol. 2018 Jun;152:293-301
J:271712 Zhang T, et al., Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity. Theranostics. 2018;8(19):5246-5258
J:295468 Xu X, et al., PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter. FASEB J. 2020 May;34(5):6479-6492