Sequence Detail

ID/Version

O08605 (UniProt | EBI)

Last sequence update: 2003-04-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 1; EC=2.7.11.1 {ECO:0000269|PubMed:9155017};AltName: Full=MAP kinase signal-integrating kinase 1; Short=MAPK signal-integrating kinase 1; Short=Mnk1;

Provider

SWISS-PROT

Sequence

Polypeptide 427 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mknk1	MAP kinase-interacting serine/threonine kinase 1	33	103	3	11

Sequence references in MGI

J:40024 Waskiewicz AJ, et al., Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J. 1997 Apr 15;16(8):1909-20
J:92819 Orton KC, et al., Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. J Biol Chem. 2004 Sep 10;279(37):38649-57
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89