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Sequence Detail
O08601 Q91X33 Q3UJA0 B2CXA7 (UniProt | EBI) Last sequence update: 2010-01-19
Last annotation update: 2018-05-23
from provider
RecName: Full=Microsomal triglyceride transfer protein large subunit;Flags: Precursor;
Polypeptide 894 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Mttp microsomal triglyceride transfer protein 34 5 9 16
Sequence references in MGI J:32784 Nakamuta M, et al., Mouse microsomal triglyceride transfer protein large subunit: cDNA cloning, tissue-specific expression and chromosomal localization. Genomics. 1996 Apr 15;33(2):313-6
J:61175 Leung GK, et al., A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion. J Biol Chem. 2000 Mar 17;275(11):7515-20
J:61562 Shelton JM, et al., Microsomal triglyceride transfer protein expression during mouse development. J Lipid Res. 2000 Apr;41(4):532-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124933 Mohler PJ, et al., Identification of a novel isoform of microsomal triglyceride transfer protein. J Biol Chem. 2007 Sep 14;282(37):26981-8
J:125365 Dougan SK, et al., MTP regulated by an alternate promoter is essential for NKT cell development. J Exp Med. 2007 Mar 19;204(3):533-45
J:137715 Kamagate A, et al., FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice. J Clin Invest. 2008 Jun;118(6):2347-64
J:138737 Iqbal J, et al., Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition. J Biol Chem. 2008 Jul 18;283(29):19967-80
J:216037 Wang F, et al., LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver. J Mol Endocrinol. 2014 Apr;52(2):133-43

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last database update
MGI 6.12
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