Sequence Detail

ID/Version

O08575 A2A5S4 P97925 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Eyes absent homolog 2; EC=3.1.3.48 {ECO:0000269|PubMed:14628052};

Provider

SWISS-PROT

Sequence

Polypeptide 532 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Eya2	EYA transcriptional coactivator and phosphatase 2	24	115	3	5

Sequence references in MGI

J:38379 Xu PX, et al., Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 1997 Jan;124(1):219-31
J:38486 Zimmerman JE, et al., Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Res. 1997 Feb;7(2):128-41
J:41373 Duncan MK, et al., Eyes absent: a gene family found in several metazoan phyla. Mamm Genome. 1997 Jul;8(7):479-85
J:86608 Rayapureddi JP, et al., Eyes absent represents a class of protein tyrosine phosphatases. Nature. 2003 Nov 20;426(6964):295-8
J:112682 Hata S, et al., Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP. J Biol Chem. 2006 Apr 21;281(16):11214-24
J:113793 Ohto H, et al., Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. Mol Cell Biol. 1999 Oct;19(10):6815-24
J:119948 Grifone R, et al., Eya1 and Eya2 proteins are required for hypaxial somitic myogenesis in the mouse embryo. Dev Biol. 2007 Feb 15;302(2):602-16