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Sequence Detail
ID/Version
G3X912 B2RY42 (UniProt | EBI) Last sequence update: 2011-11-16
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=DNA-dependent metalloprotease SPRTN {ECO:0000305}; EC=3.4.24.- {ECO:0000250|UniProtKB:Q9H040};AltName: Full=Protein with SprT-like domain at the N terminus {ECO:0000250|UniProtKB:Q9H040}; Short=Spartan {ECO:0000250|UniProtKB:
Provider SWISS-PROT
Sequence
Polypeptide 497 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sprtn SprT-like N-terminal domain 35 96 3 6
Sequence references in MGI J:225198 Maskey RS, et al., Spartan deficiency causes genomic instability and progeroid phenotypes. Nat Commun. 2014;5:5744
J:246108 Maskey RS, et al., Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017 May 05;45(8):4564-4576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory