Sequence Detail

ID/Version

G3X912 B2RY42 (UniProt | EBI)

Last sequence update: 2011-11-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA-dependent metalloprotease SPRTN {ECO:0000305}; EC=3.4.24.- {ECO:0000250|UniProtKB:Q9H040};AltName: Full=Protein with SprT-like domain at the N terminus {ECO:0000250|UniProtKB:Q9H040}; Short=Spartan {ECO:0000250|UniProtKB:

Provider

SWISS-PROT

Sequence

Polypeptide 497 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sprtn	SprT-like N-terminal domain	69	96	3	6

Sequence references in MGI

J:225198 Maskey RS, et al., Spartan deficiency causes genomic instability and progeroid phenotypes. Nat Commun. 2014;5:5744
J:246108 Maskey RS, et al., Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017 May 05;45(8):4564-4576