Sequence Detail

ID/Version

G3UXB3 (UniProt | EBI)

Last sequence update: 2022-02-23
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=NK1 transcription factor-related protein 1 {ECO:0000305};AltName: Full=Homeobox protein SAX-2;AltName: Full=NKX-1.1;

Provider

SWISS-PROT

Sequence

Polypeptide 440 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nkx1-1	NK1 homeobox 1	15	97	3	8

Sequence references in MGI

J:86868 Simon R, et al., Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60
J:125509 Simon R, et al., Homeobox gene Sax2 deficiency causes an imbalance in energy homeostasis. Dev Dyn. 2007 Oct;236(10):2792-9
J:179192 Simon R, et al., Ablation of Sax2 gene expression prevents diet-induced obesity. FEBS J. 2011 Jan;278(2):371-82