Sequence Detail

ID/Version

P01108 Q3UM70 F8WID3 Q61422 B2RSN1 F6PX41 P70247 A0A087WSQ0 (UniProt | EBI)

Last sequence update: 2023-02-22
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Myc proto-oncogene protein;AltName: Full=Proto-oncogene c-Myc;AltName: Full=Transcription factor p64;

Provider

SWISS-PROT

Sequence

Polypeptide 454 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Myc	myelocytomatosis oncogene	229	185	4	90

Sequence references in MGI

J:7180 Neuberger MS, et al., Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes. Nature. 1983 Sep 15-21;305(5931):240-3
J:7520 Stanton LW, et al., Nucleotide sequence comparison of normal and translocated murine c-myc genes. Nature. 1984 Aug 2-8;310(5976):423-5
J:29949 Hurlin PJ, et al., Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J. 1995 Nov 15;14(22):5646-59
J:30475 Bernard O, et al., Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours. EMBO J. 1983;2(12):2375-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:165016 Lee CM, et al., JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14189-94
J:177147 Zhang Y, et al., Pim kinase-dependent inhibition of c-Myc degradation. Oncogene. 2008 Aug 14;27(35):4809-19
J:184685 Wilson CH, et al., Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation. EMBO J. 2012;31(11):2486-97
J:197300 Sato T, et al., TRIM6 interacts with Myc and maintains the pluripotency of mouse embryonic stem cells. J Cell Sci. 2012 Mar 15;125(Pt 6):1544-55
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:278440 Seruggia D, et al., TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network. Mol Cell. 2019 Jun 20;74(6):1148-1163.e7