Sequence Detail

ID/Version

F8VQ03 (UniProt | EBI)

Last sequence update: 2011-09-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=A disintegrin and metallopeptidase domain 3 {ECO:0000312|MGI:MGI:102518};AltName: Full=Cyritestin {ECO:0000312|MGI:MGI:102518};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 822 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adam3	ADAM metallopeptidase domain 3	32	96	2	9

Sequence references in MGI

J:147330 Yamaguchi R, et al., Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse. Biol Reprod. 2009 Jul;81(1):142-6
J:197323 Fujihara Y, et al., Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8111-6
J:210341 Fujihara Y, et al., GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice. Biol Reprod. 2014 Mar;90(3):60
J:243404 Kim E, et al., Synthesis, processing, and subcellular localization of mouse ADAM3 during spermatogenesis and epididymal sperm transport. J Reprod Dev. 2004 Oct;50(5):571-8
J:293874 Larasati T, et al., Tmprss12 is required for sperm motility and uterotubal junction migration in mice. Biol Reprod. 2020 Aug 4;103(2):254-263
J:341385 Han C, et al., Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm. J Cell Physiol. 2011 May;226(5):1186-95