Sequence Detail

ID/Version

E9Q7G0 Q80Y35 (UniProt | EBI)

Last sequence update: 2011-04-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Nuclear mitotic apparatus protein 1 {ECO:0000250|UniProtKB:Q14980};AltName: Full=Nuclear mitotic apparatus protein {ECO:0000250|UniProtKB:Q14980}; Short=NuMA protein {ECO:0000250|UniProtKB:Q14980};

Provider

SWISS-PROT

Sequence

Polypeptide 2094 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Numa1	nuclear mitotic apparatus protein 1	108	106	3	91

Sequence references in MGI

J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:146214 Silk AD, et al., Requirements for NuMA in maintenance and establishment of mammalian spindle poles. J Cell Biol. 2009 Mar 9;184(5):677-90
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:229900 Seldin L, et al., NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures. Elife. 2016;5:e12504
J:239972 Chiu CW, et al., SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Galphai-LGN-NuMA Ternary Complex. Dev Cell. 2016 Jan 11;36(1):50-62
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306588 Zhao B, et al., Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability. Cell Stem Cell. 2015 Jun 4;16(6):684-98