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Sequence Detail
E9Q401 Q62197 Q62174 Q9ERN6 O70181 (UniProt | EBI) Last sequence update: 2011-04-05
Last annotation update: 2018-04-25
from provider
RecName: Full=Ryanodine receptor 2; Short=RYR-2; Short=RyR2;AltName: Full=Cardiac muscle ryanodine receptor;AltName: Full=Cardiac muscle ryanodine receptor-calcium release channel;AltName: Full=Type 2 ryanodine receptor;
Polypeptide 4966 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Ryr2 ryanodine receptor 2, cardiac 117 13 10 57
Sequence references in MGI J:23314 Giannini G, et al., The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. J Cell Biol. 1995 Mar;128(5):893-904
J:26886 Takeshima H, et al., Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor. EMBO J. 1995 Jul 3;14(13):2999-3006
J:48277 Takeshima H, et al., Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J. 1998 Jun 15;17(12):3309-16
J:57615 Zhao M, et al., Molecular identification of the ryanodine receptor pore-forming segment. J Biol Chem. 1999 Sep 10;274(37):25971-4
J:179475 van Oort RJ, et al., Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation. 2010 Dec 21;122(25):2669-79

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory