Sequence Detail

ID/Version

E9Q394 Q3UEI5 (UniProt | EBI)

Last sequence update: 2011-04-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=A-kinase anchor protein 13; Short=AKAP-13;AltName: Full=AKAP-Lbc {ECO:0000303|PubMed:17537920};

Provider

SWISS-PROT

Sequence

Polypeptide 2776 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Akap13	A kinase anchor protein 13	46	101	4	67

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111574 Kino T, et al., Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. J Biol Chem. 2006 Apr 7;281(14):9118-26
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:181087 Mayers CM, et al., The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem. 2010 Apr 16;285(16):12344-54
J:231257 Spindler MJ, et al., AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to beta-adrenergic-induced cardiac hypertrophy. (RETRACTION PLoS ONE 18(12): e0296004). PLoS One. 2013;8(4):e62705
J:231274 Smith FD, et al., AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol. 2010 Dec;12(12):1242-9
J:231357 Koide H, et al., Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis. J Bone Miner Res. 2015 Oct;30(10):1887-95
J:238039 Taglieri DM, et al., The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy. J Mol Cell Cardiol. 2014 Jan;66:27-40
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89