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Sequence Detail
ID/Version
E9PVX6 Q61769 Q7TSF6 (UniProt | EBI) Last sequence update: 2011-04-05
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Proliferation marker protein Ki-67 {ECO:0000305};AltName: Full=Antigen identified by monoclonal antibody Ki-67 homolog {ECO:0000305}; Short=Antigen KI-67 homolog {ECO:0000305}; Short=Antigen Ki67 homolog {ECO:0000305};
Provider SWISS-PROT
Sequence
Polypeptide 3177 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Mki67 antigen identified by monoclonal antibody Ki 67 37 520 3 20
Sequence references in MGI J:31173 Starborg M, et al., The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression. J Cell Sci. 1996 Jan;109(Pt 1):143-53
J:80451 Traut W, et al., The temporal and spatial distribution of the proliferation associated Ki-67 protein during female and male meiosis. Chromosoma. 2002 Sep;111(3):156-64
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:235309 Sobecki M, et al., The cell proliferation antigen Ki-67 organises heterochromatin. Elife. 2016;5:e13722
J:235728 Cuylen S, et al., Ki-67 acts as a biological surfactant to disperse mitotic chromosomes. Nature. 2016 Jul 14;535(7611):308-12
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:352604 Sanz-Flores M, et al., PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis. Cell Rep. 2024 Jul 23;43(7):114494

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory