Sequence Detail

ID/Version

D3Z2R5 (UniProt | EBI)

Last sequence update: 2016-04-13
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Selenoprotein N {ECO:0000303|PubMed:21131290}; Short=SelN {ECO:0000303|PubMed:21131290};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 557 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Selenon	selenoprotein N	26	110	3	9

Sequence references in MGI

J:168699 Castets P, et al., Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency. Hum Mol Genet. 2011 Feb 15;20(4):694-704
J:176499 Rederstorff M, et al., Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy. PLoS One. 2011;6(8):e23094
J:219362 Marino M, et al., SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity. Hum Mol Genet. 2015 Apr 1;24(7):1843-55