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Sequence Detail
ID/Version
D3Z291 (UniProt | EBI) Last sequence update: 2010-04-20
Last annotation update: 2021-06-02
Sequence
description
from provider
RecName: Full=Calcium homeostasis modulator protein 1;
Provider SWISS-PROT
Sequence
Polypeptide 348 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Calhm1 calcium homeostasis modulator 1 27 88 3 4
Sequence references in MGI J:186424 Ma Z, et al., Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1963-71
J:194915 Taruno A, et al., CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature. 2013 Mar 14;495(7440):223-6
J:244828 Wu J, et al., Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression. Protein Cell. 2012 Jun;3(6):470-80
J:269649 Ma Z, et al., CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Neuron. 2018 May 2;98(3):547-561.e10
J:286883 Kashio M, et al., CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells. Sci Rep. 2019 Feb 25;9(1):2681

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory