Sequence Detail

ID/Version

B9EKR1 (UniProt | EBI)

Last sequence update: 2009-03-24
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Receptor-type tyrosine-protein phosphatase zeta; Short=R-PTP-zeta; EC=3.1.3.48 {ECO:0000269|PubMed:16513268};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2312 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptprz1	protein tyrosine phosphatase receptor type Z, polypeptide 1	74	154	4	11

Sequence references in MGI

J:64776 Harroch S, et al., No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta. Mol Cell Biol. 2000 Oct;20(20):7706-15
J:79860 Harroch S, et al., A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions. Nat Genet. 2002 Nov;32(3):411-4
J:85827 Shintani T, et al., Neurons as well as astrocytes express proteoglycan-type protein tyrosine phosphatase zeta/RPTPbeta: analysis of mice in which the PTPzeta/RPTPbeta gene was replaced with the LacZ gene. Neurosci Lett. 1998 May 15;247(2-3):135-8
J:107976 Tamura H, et al., Protein tyrosine phosphatase receptor type Z is involved in hippocampus-dependent memory formation through dephosphorylation at Y1105 on p190 RhoGAP. Neurosci Lett. 2006 May 15;399(1-2):33-8
J:157543 Bouyain S, et al., The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2443-8
J:177481 Lamprianou S, et al., A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17498-503
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89