Sequence Detail

ID/Version

B7ZNG0 B2RUB1 (UniProt | EBI)

Last sequence update: 2009-03-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Kinesin-like protein KIF7;

Provider

SWISS-PROT

Sequence

Polypeptide 1348 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kif7	kinesin family member 7	30	102	3	11

Sequence references in MGI

J:151965 Liem KF Jr, et al., Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13377-82
J:152259 Cheung HO, et al., The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal. 2009;2(76):ra29
J:152551 Endoh-Yamagami S, et al., The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol. 2009 Aug 11;19(15):1320-6
J:175769 Hsu SH, et al., Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801
J:189074 Li ZJ, et al., Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61
J:218232 Chong YC, et al., Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5. Genes Dev. 2015 Feb 1;29(3):262-76
J:219388 He M, et al., The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment. Nat Cell Biol. 2014 Jul;16(7):663-72
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89