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Sequence Detail
ID/Version
Q3UL53 B6ZND8 B6ZND9 (UniProt | EBI) Last sequence update: 2005-10-11
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Homeobox protein Crxos {ECO:0000305};AltName: Full=Cone-rod homeobox, opposite strand protein {ECO:0000305};AltName: Full=Expressing gene at morula stage protein 1 {ECO:0000303|PubMed:20018908}; Short=EGAM1 {ECO:0000303|PubMed:200189
Provider SWISS-PROT
Sequence
Polypeptide 246 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Crxos cone-rod homeobox, opposite strand 14 104 0 10
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:159743 Saito K, et al., Cloning of complementary DNAs encoding structurally related homeoproteins from preimplantation mouse embryos: their involvement in the differentiation of embryonic stem cells. Biol Reprod. 2010 Apr;82(4):687-97
J:180846 Saito K, et al., Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68
J:344763 Sato S, et al., Intact structure of EGAM1 homeoproteins and basic amino acid residues in the common homeodomain of EGAM1 and EGAM1C contribute to their nuclear localization in mouse embryonic stem cells. J Biosci Bioeng. 2013 Aug;116(2):141-6
J:345042 Soma M, et al., Preferential emergence of cell types expressing markers for primitive endoderm lineages in mouse embryonic stem cells expressing exogenous EGAM1 homeoprotein. J Biosci Bioeng. 2012 Sep;114(3):342-6
J:345167 Sato S, et al., Partial inhibition of differentiation associated with elevated protein levels of pluripotency factors in mouse embryonic stem cells expressing exogenous EGAM1N homeoprotein. J Biosci Bioeng. 2015 Nov;120(5):562-9
J:345436 Iha M, et al., Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells. Reproduction. 2012 Apr;143(4):477-89
J:345442 Iha M, et al., Severe inhibition of in vitro cardiomyogenesis in mouse embryonic stem cells ectopically expressing EGAM1C homeoprotein. Biosci Biotechnol Biochem. 2012;76(7):1410-2
J:345779 Saito R, et al., CrxOS maintains the self-renewal capacity of murine embryonic stem cells. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1129-35

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory