Sequence Detail

ID/Version

B1AXD8 Q9DAH4 Q641L8 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Akirin-2 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 201 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Akirin2	akirin 2	64	97	3	17

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130487 Goto A, et al., Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol. 2008 Jan;9(1):97-104
J:216064 Tartey S, et al., Akirin2 is critical for inducing inflammatory genes by bridging IkappaB-zeta and the SWI/SNF complex. EMBO J. 2014 Oct 16;33(20):2332-48
J:237195 Bosch PJ, et al., Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016 Nov 21;11(1):21
J:275243 Bosch PJ, et al., A critical role for the nuclear protein Akirin2 in the formation of mammalian muscle in vivo. Genesis. 2019 May;57(5):e23286
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:316302 Bosch PJ, et al., An essential role for the nuclear protein Akirin2 in mouse limb interdigital tissue regression. Sci Rep. 2018 Aug 16;8(1):12240
J:322367 Tartey S, et al., Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses. J Immunol. 2015 Jul 15;195(2):519-27