Sequence Detail

ID/Version

A4Q9F0 A4Q9E9 Q9D5V3 Q8C417 (UniProt | EBI)

Last sequence update: 2007-05-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tubulin polyglutamylase TTLL7 {ECO:0000305|PubMed:17499049}; EC=6.3.2.- {ECO:0000269|PubMed:16901895, ECO:0000269|PubMed:17499049, ECO:0000269|PubMed:19152315};AltName: Full=Tubulin--tyrosine ligase-like protein 7 {ECO:0000305|PubMed

Provider

SWISS-PROT

Sequence

Polypeptide 912 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttll7	tubulin tyrosine ligase-like family, member 7	34	97	3	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117216 Ikegami K, et al., TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites. J Biol Chem. 2006 Oct 13;281(41):30707-16
J:130247 van Dijk J, et al., A targeted multienzyme mechanism for selective microtubule polyglutamylation. Mol Cell. 2007 May 11;26(3):437-48
J:149071 Mukai M, et al., Recombinant mammalian tubulin polyglutamylase TTLL7 performs both initiation and elongation of polyglutamylation on beta-tubulin through a random sequential pathway. Biochemistry. 2009 Feb 10;48(5):1084-93