Sequence Detail

ID/Version

A4Q9E5 Q8C0Y7 Q8BV51 Q8VDS2 (UniProt | EBI)

Last sequence update: 2007-05-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Tubulin monoglycylase TTLL3 {ECO:0000303|PubMed:19524510}; EC=6.3.2.- {ECO:0000269|PubMed:19524510};AltName: Full=Tubulin--tyrosine ligase-like protein 3 {ECO:0000303|PubMed:19524510};

Provider

SWISS-PROT

Sequence

Polypeptide 927 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttll3	tubulin tyrosine ligase-like family, member 3	22	99	3	34

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130247 van Dijk J, et al., A targeted multienzyme mechanism for selective microtubule polyglutamylation. Mol Cell. 2007 May 11;26(3):437-48
J:150280 Rogowski K, et al., Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. Cell. 2009 Jun 12;137(6):1076-87
J:201638 Bosch Grau M, et al., Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia. J Cell Biol. 2013 Aug 5;202(3):441-51
J:216383 Rocha C, et al., Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon. EMBO J. 2014 Oct 1;33(19):2247-60
J:300009 Gadadhar S, et al., Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science. 2021 Jan 8;371(6525)