Sequence Detail

ID/Version

A3KGV1 O35496 A3KGV5 Q3TH68 A3KGV6 O35135 Q6PGI6 Q3UP80 (UniProt | EBI)

Last sequence update: 2007-04-03
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Outer dense fiber protein 2;AltName: Full=84 kDa outer dense fiber protein;AltName: Full=Cenexin;AltName: Full=Outer dense fiber of sperm tails protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 830 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Odf2	outer dense fiber of sperm tails 2	32	106	4	24

Sequence references in MGI

J:39266 Shao X, et al., Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27. J Biol Chem. 1997 Mar 7;272(10):6105-13
J:49572 Hoyer-Fender S, et al., Mouse Odf2 cDNAs consist of evolutionary conserved as well as highly variable sequences and encode outer dense fiber proteins of the sperm tail. Mol Reprod Dev. 1998 Oct;51(2):167-75
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:207807 Kodani A, et al., Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages. EMBO J. 2013 Feb 20;32(4):597-607
J:263397 Wang X, et al., Testis-specific serine/threonine protein kinase 4 (Tssk4) phosphorylates Odf2 at Ser-76. Sci Rep. 2016 Mar 10;6:22861
J:263443 Wang X, et al., Tssk4 is essential for maintaining the structural integrity of sperm flagellum. Mol Hum Reprod. 2015 Feb;21(2):136-45
J:265626 Zhang Z, et al., Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice. Mol Biol Cell. 2016 Sep 28;
J:273640 Camargo Ortega G, et al., The centrosome protein AKNA regulates neurogenesis via microtubule organization. Nature. 2019 Mar;567(7746):113-117
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304729 Li ZZ, et al., The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Biosci Rep. 2020 Jan 31;40(1)
J:323414 Ishikawa H, et al., Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia. Nat Cell Biol. 2005 May;7(5):517-24
J:343412 Cao H, et al., BBOF1 is required for sperm motility and male fertility by stabilizing the flagellar axoneme in mice. Cell Mol Life Sci. 2023 May 17;80(6):152