Sequence Detail

ID/Version

E9Q8Q6 A2AST1 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Coiled-coil domain-containing protein 141;AltName: Full=Coiled-coil protein associated with myosin II and DISC1 {ECO:0000303|PubMed:20956536};

Provider

SWISS-PROT

Sequence

Polypeptide 1531 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ccdc141	coiled-coil domain containing 141	7	102	3	12

Sequence references in MGI

J:167582 Fukuda T, et al., CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration. J Biol Chem. 2010 Dec 24;285(52):40554-61
J:238090 Fukuda T, et al., Rescue of CAMDI deletion-induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor. EMBO Rep. 2016 Dec;17(12):1785-1798
J:261733 Hutchins BI, et al., CCDC141 Mutation Identified in Anosmic Hypogonadotropic Hypogonadism (Kallmann Syndrome) Alters GnRH Neuronal Migration. Endocrinology. 2016 May;157(5):1956-66
J:282174 Fukuda T, et al., CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition. PLoS One. 2019;14(11):e0224967
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:338234 Okuda S, et al., Oscillation of Cdc20-APC/C-mediated CAMDI stability is critical for cortical neuron migration. J Biol Chem. 2021 Jul 21;297(2):100986