Sequence Detail

ID/Version

A2ASS6 A2ASS5 A2ASS7 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Titin; EC=2.7.11.1;AltName: Full=Connectin;

Provider

SWISS-PROT

Sequence

Polypeptide 35213 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttn	titin	83	140	3	34

Sequence references in MGI

J:45834 Gautel M, et al., Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle. Circ Res. 1998 Jan 9-23;82(1):124-9
J:111284 Weinert S, et al., M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol. 2006 May 22;173(4):559-70
J:132331 Peng J, et al., Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region. Circulation. 2007 Feb 13;115(6):743-51
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87