Sequence Detail

ID/Version

A2AKX3 Q8C859 A2AKX4 Q8C5P1 A2AR33 Q8C8P6 Q6ZQ81 Q6PED8 Q6IMG6 Q80V90 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Probable helicase senataxin {ECO:0000305}; EC=3.6.4.-;AltName: Full=Amyotrophic lateral sclerosis 4 protein homolog;AltName: Full=SEN1 homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 2646 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Setx	senataxin	72	99	3	47

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:185950 Padmanabhan K, et al., Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science. 2012 Aug 3;337(6094):599-602
J:223053 Becherel OJ, et al., Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing. PLoS Genet. 2013 Apr;9(4):e1003435
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89