Sequence Detail

ID/Version

Q60988 Q8C7U6 Q99KL4 Q80VK7 Q8CEL7 A2AD39 (UniProt | EBI)

Last sequence update: 2024-01-24
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=SCL-interrupting locus protein homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 1262 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stil	Scl/Tal1 interrupting locus	50	99	3	11

Sequence references in MGI

J:30580 Collazo-Garcia N, et al., Cloning and characterization of a murine SIL gene. Genomics. 1995 Dec 10;30(3):506-13
J:30658 Aplan PD, et al., Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia. Mol Cell Biol. 1991 Nov;11(11):5462-9
J:55887 Izraeli S, et al., The SIL gene is required for mouse embryonic axial development and left-right specification. Nature. 1999 Jun 17;399(6737):691-4
J:68016 Gottgens B, et al., Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences. Genome Res. 2001 Jan;11(1):87-97
J:72500 Izraeli S, et al., Genetic evidence that Sil is required for the sonic hedgehog response pathway. Genesis. 2001 Oct;31(2):72-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100018 Campaner S, et al., Sil phosphorylation in a pin1 binding domain affects the duration of the spindle checkpoint. Mol Cell Biol. 2005 Aug;25(15):6660-72