Sequence Detail

ID/Version

A2A9C3 Q7TSS6 Q6PB77 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=KICSTOR complex protein SZT2 {ECO:0000305};AltName: Full=Seizure threshold 2 protein {ECO:0000303|PubMed:19624305};AltName: Full=Transcript increased in glutamate resistance {ECO:0000303|PubMed:20045724}; Short=TIGR {ECO:0000303|PubM

Provider

SWISS-PROT

Sequence

Polypeptide 3431 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Szt2	SZT2 subunit of KICSTOR complex	26	104	3	12

Sequence references in MGI

J:150942 Frankel WN, et al., Szt2, a novel gene for seizure threshold in mice. Genes Brain Behav. 2009 Jul;8(5):568-76
J:205670 Toutzaris D, et al., A novel giant peroxisomal superoxide dismutase motif-containing protein. Free Radic Biol Med. 2010 Mar 15;48(6):811-20
J:240399 Wolfson RL, et al., KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017 Mar 16;543(7645):438-442
J:241016 Peng M, et al., SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017 Mar 16;543(7645):433-437
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89