Sequence Detail

ID/Version

A2A8L1 Q6ZQB2 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Chromodomain-helicase-DNA-binding protein 5; Short=CHD-5; EC=3.6.4.12;AltName: Full=ATP-dependent helicase CHD5;

Provider

SWISS-PROT

Sequence

Polypeptide 1946 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chd5	chromodomain helicase DNA binding protein 5	38	103	3	12

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:121726 Bagchi A, et al., CHD5 is a tumor suppressor at human 1p36. Cell. 2007 Feb 9;128(3):459-75
J:204443 Egan CM, et al., CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression. Dev Cell. 2013 Aug 12;26(3):223-36
J:207808 Paul S, et al., Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell Rep. 2013 Jan 31;3(1):92-102
J:207814 Potts RC, et al., CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS One. 2011;6(9):e24515
J:207846 Zhuang T, et al., CHD5 is required for spermiogenesis and chromatin condensation. Mech Dev. 2014 Feb;131:35-46
J:240892 Nitarska J, et al., A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89