Sequence Detail

ID/Version

A0A494BA31 (UniProt | EBI)

Last sequence update: 2019-06-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Anion exchange protein 4 {ECO:0000305}; Short=AE 4; Short=Anion exchanger 4;AltName: Full=Solute carrier family 4 member 9;

Provider

SWISS-PROT

Sequence

Polypeptide 952 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc4a9	solute carrier family 4, sodium bicarbonate cotransporter, member 9	38	98	2	7

Sequence references in MGI

J:121543 Simpson JE, et al., PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1079-88
J:197347 Chambrey R, et al., Renal intercalated cells are rather energized by a proton than a sodium pump. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7928-33
J:222176 Pena-Munzenmayer G, et al., Ae4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells. J Biol Chem. 2015 Apr 24;290(17):10677-88
J:331519 Pena-Munzenmayer G, et al., Activation of the Ae4 (Slc4a9) cation-driven Cl(-)/HCO(3)(-) exchanger by the cAMP-dependent protein kinase in salivary gland acinar cells. Am J Physiol Gastrointest Liver Physiol. 2021 Dec 1;321(6):G628-G638
J:335609 Pena-Munzenmayer G, et al., Ae4 (Slc4a9) is an electroneutral monovalent cation-dependent Cl-/HCO3- exchanger. J Gen Physiol. 2016 May;147(5):423-36
J:335662 Ko SB, et al., AE4 is a DIDS-sensitive Cl(-)/HCO(-)(3) exchanger in the basolateral membrane of the renal CCD and the SMG duct. Am J Physiol Cell Physiol. 2002 Oct;283(4):C1206-18