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Mammalian Phenotype Browser
Term Detail
MP term:glomerular crescent
MP id: MP:0011506
Definition: formation of a crescent-shaped (semi-lunar) glomerular lesion corresponding to extracapillary proliferation of Bowman's capsular epithelium and acquiring a fibroblast-like spindled morphology, possibly stimulated by release of fibrinogen from a ruptured glomerular basement membrane; epithelial crescents occur in aggressive forms of glomerulonephritis, may be accompanied by collagen and fibrin deposition and/or monocyte and macrophage proliferation, may protrude into Bowman's space, and ultimately compress and destroy the glomerular tuft
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal kidney cortex morphology
                                        is-aabnormal renal corpuscle morphology
                                                is-aabnormal renal glomerulus morphology
                                                        is-aabnormal glomerular capillary morphology +
                                                        is-aabnormal glomerular filtration barrier morphology
                                                        is-aabnormal glomerular mesangium morphology +
                                                        is-aabsent renal glomerulus
                                                        is-acortical renal glomerulopathies +
                                                        is-adecreased renal glomerulus number
                                                        is-aglomerular crescent [MP:0011506] (23 genotypes, 23 annotations)
                                                        is-aincreased renal glomerulus lobularity
                                                        is-arenal glomerular synechia
                                                        is-arenal glomerulus atrophy
                                                        is-arenal glomerulus fibrosis
                                                        is-arenal glomerulus hypertrophy
                                                        is-arenal glomerulus lipidosis


mammalian phenotype
        is-arenal/urinary system phenotype
                is-aabnormal renal/urinary system morphology
                        is-aabnormal kidney morphology
                                is-aabnormal nephron morphology
                                        is-aabnormal renal corpuscle morphology
                                                is-aabnormal renal glomerulus morphology
                                                        is-aabnormal glomerular capillary morphology +
                                                        is-aabnormal glomerular filtration barrier morphology
                                                        is-aabnormal glomerular mesangium morphology +
                                                        is-aabsent renal glomerulus
                                                        is-acortical renal glomerulopathies +
                                                        is-adecreased renal glomerulus number
                                                        is-aglomerular crescent [MP:0011506] (23 genotypes, 23 annotations)
                                                        is-aincreased renal glomerulus lobularity
                                                        is-arenal glomerular synechia
                                                        is-arenal glomerulus atrophy
                                                        is-arenal glomerulus fibrosis
                                                        is-arenal glomerulus hypertrophy
                                                        is-arenal glomerulus lipidosis

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory