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MP term:decreased susceptibility to dopaminergic neuron neurotoxicity
Synonym: decreased susceptibility to dopamine neuron neurotoxicity
Synonym: reduced susceptibility to dopamine neuron neurotoxicity
Synonym: reduced susceptibility to dopaminergic neuron neurotoxicity
MP id: MP:0011452
Definition: less than normal amount of dopaminergic neuronal cell death following exposure to a neurotoxic compound, such as MPTP-induced cell death occurring through interference in mitochondrial metabolism
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-aabnormal apoptosis
                                        is-aabnormal neuron apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity [MP:0011452] (19 genotypes, 19 annotations)


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-aabnormal apoptosis
                                        is-adecreased apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity [MP:0011452] (19 genotypes, 19 annotations)


mammalian phenotype
        is-acellular phenotype
                is-aabnormal cell physiology
                        is-aabnormal cell death
                                is-adecreased cell death
                                        is-adecreased apoptosis
                                                is-adecreased neuron apoptosis
                                                        is-adecreased susceptibility to neuronal excitotoxicity
                                                                is-adecreased susceptibility to dopaminergic neuron neurotoxicity [MP:0011452] (19 genotypes, 19 annotations)


mammalian phenotype
        is-ahomeostasis/metabolism phenotype
                is-aabnormal physiological response to xenobiotic
                        is-adecreased physiological sensitivity to xenobiotic
                                is-adecreased susceptibility to neuronal excitotoxicity
                                        is-adecreased susceptibility to dopaminergic neuron neurotoxicity [MP:0011452] (19 genotypes, 19 annotations)


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal neuron physiology
                                is-aabnormal neuron apoptosis
                                        is-adecreased neuron apoptosis
                                                is-adecreased susceptibility to neuronal excitotoxicity
                                                        is-adecreased susceptibility to dopaminergic neuron neurotoxicity [MP:0011452] (19 genotypes, 19 annotations)

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory