MGI 5.13 - Phenotype Browser

Mammalian Phenotype Browser
Term Detail

MP term:	abnormal renal glomerulus basement membrane morphology
Synonym:	abnormal GBM morphology
Synonym:	abnormal glomerular basement membrane morphology
Synonym:	abnormal glomerulus basement membrane morphology
Synonym:	abnormal kidney glomerulus basement membrane morphology
MP id:	MP:0011348
Definition:	any structural anomaly of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter
Number of paths to term:	2

denotes an 'is-a' relationship
denotes a 'part-of' relationship

mammalian phenotype

renal/urinary system phenotype

abnormal renal/urinary system morphology

abnormal kidney morphology

abnormal kidney cortex morphology

abnormal renal corpuscle morphology

abnormal extraglomerular mesangium morphology +

abnormal kidney afferent arteriole morphology

abnormal kidney efferent arteriole morphology

abnormal renal glomerular capsule morphology +

abnormal renal glomerulus basement membrane morphology [MP:0011348] (68 genotypes, 89 annotations)

abnormal renal glomerulus basement membrane thickness +