| MP term: | decreased solitary pulmonary neuroendocrine cell number |
| Synonym: | decreased bronchiolar Kulchitsky cell number |
| Synonym: | decreased Feyrter cell number |
| Synonym: | decreased Kulschitzky cells |
| Synonym: | decreased Kultschitzky cell of bronchiole number |
| Synonym: | decreased P cell number |
| Synonym: | decreased PNECs |
| Synonym: | decreased respiratory enterochromaffin cell number |
| Synonym: | decreased single pulmonary neuroendocrine cell number |
| Synonym: | reduced bronchiolar Kulchitsky cell number |
| Synonym: | reduced Feyrter cell number |
| Synonym: | reduced Kulschitzky cells |
| Synonym: | reduced Kultschitzky cell of bronchiole number |
| Synonym: | reduced P cell number |
| Synonym: | reduced PNECs |
| Synonym: | reduced respiratory enterochromaffin cell number |
| Synonym: | reduced single pulmonary neuroendocrine cell number |
| MP id: | MP:0010916 |
| Definition: | decreased number of the specialized non-ciliated, round- to oval-shaped epithelial cells found as solitary cells in the nasal respiratory epithelium and the mucosa of the larynx, trachea and bronchi up to the terminal bronchioles; PNECs are the first cell type to differentiate during early fetal lung development, produce amine (e.g. serotonin, 5-HT) and peptides (e.g. bombesin, calcitonin) with growth factor-like properties, and appear to be involved in processes ranging from lung development and respiratory physiology to repair, disease and carcinogenesis |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
endocrine/exocrine gland phenotypeabnormal gland morphologyabnormal neuroendocrine gland morphologyabnormal neuroendocrine cell morphologyabnormal solitary pulmonary neuroendocrine cell morphologyabsent solitary pulmonary neuroendocrine cellsdecreased solitary pulmonary neuroendocrine cell number [MP:0010916] (2 genotypes, 2 annotations)increased solitary pulmonary neuroendocrine cell numbernervous system phenotypeabnormal nervous system morphologyabnormal neuron morphologyabnormal neuroendocrine cell morphologyabnormal solitary pulmonary neuroendocrine cell morphologyabsent solitary pulmonary neuroendocrine cellsdecreased solitary pulmonary neuroendocrine cell number [MP:0010916] (2 genotypes, 2 annotations)increased solitary pulmonary neuroendocrine cell numberMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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