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Mammalian Phenotype Browser
Term Detail
MP term:decreased solitary pulmonary neuroendocrine cell number
Synonym: decreased bronchiolar Kulchitsky cell number
Synonym: decreased Feyrter cell number
Synonym: decreased Kulschitzky cells
Synonym: decreased Kultschitzky cell of bronchiole number
Synonym: decreased P cell number
Synonym: decreased PNECs
Synonym: decreased respiratory enterochromaffin cell number
Synonym: decreased single pulmonary neuroendocrine cell number
Synonym: reduced bronchiolar Kulchitsky cell number
Synonym: reduced Feyrter cell number
Synonym: reduced Kulschitzky cells
Synonym: reduced Kultschitzky cell of bronchiole number
Synonym: reduced P cell number
Synonym: reduced PNECs
Synonym: reduced respiratory enterochromaffin cell number
Synonym: reduced single pulmonary neuroendocrine cell number
MP id: MP:0010916
Definition: decreased number of the specialized non-ciliated, round- to oval-shaped epithelial cells found as solitary cells in the nasal respiratory epithelium and the mucosa of the larynx, trachea and bronchi up to the terminal bronchioles; PNECs are the first cell type to differentiate during early fetal lung development, produce amine (e.g. serotonin, 5-HT) and peptides (e.g. bombesin, calcitonin) with growth factor-like properties, and appear to be involved in processes ranging from lung development and respiratory physiology to repair, disease and carcinogenesis
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aendocrine/exocrine gland phenotype
                is-aabnormal gland morphology
                        is-aabnormal neuroendocrine gland morphology
                                is-aabnormal neuroendocrine cell morphology
                                        is-aabnormal solitary pulmonary neuroendocrine cell morphology
                                                is-aabsent solitary pulmonary neuroendocrine cells
                                                is-adecreased solitary pulmonary neuroendocrine cell number [MP:0010916] (2 genotypes, 2 annotations)
                                                is-aincreased solitary pulmonary neuroendocrine cell number


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal neuroendocrine cell morphology
                                        is-aabnormal solitary pulmonary neuroendocrine cell morphology
                                                is-aabsent solitary pulmonary neuroendocrine cells
                                                is-adecreased solitary pulmonary neuroendocrine cell number [MP:0010916] (2 genotypes, 2 annotations)
                                                is-aincreased solitary pulmonary neuroendocrine cell number

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory